Dodging and burning and masking and using other photo-related tools with a mouse and keyboard feels like I'm producing a very calculated photograph. Using a stylus and multi-touch screen feels closer to the original affordances of crafting and manipulating a physical photograph. For the best of both worlds, I use the iPad in Sidecar / second-screen mode so I can use keyboard shortcuts with 1:1 stylus input.
Oh, I agree about the mouse bit - but Wacom (etc.) tablets have been around forever. I’d also much rather keep my head straight and my arm at rest on my desk all day.
